Objective: This comprehensive article explores the emerging role of pharmacogenetics in optimizing treatment for chronic congenital anemias, including β-thalassemia, sickle cell disease (SCD), and rare erythropoietic disorders. It integrates a systematic review with an in-depth clinical analysis of …

In a world where every click can be turned into profit, children are becoming the protagonists of a digital transformation that is fundamentally changing the definition of work and the relationship between childhood and technology. This has created a new landscape where the lack of legal protection …

The management of Class II malocclusions accompanied by midline deviation requires individualized approaches that balance treatment effectiveness with patient tolerance to orthodontic appliances. The Pendulum appliance is a fixed orthodontic device known as an effective and reliable method for maxil…

Dental implants have become a primary treatment modality in daily clinical practice. Due to their high long-term survival rates, they are now considered the preferred option for prosthetic rehabilitation in many clinical situations. Although they require relatively long treatment time and it comes w…

TWIN-BLOCK is a removable orthodontic appliance designed by W. Clark in 1977. Is frequently used in the treatment of second class orthodontic anomalies with mandibular deficiency. In contemporary literature very little has been reported for the use of this functional appliance therefore, the main go…

This clinical article highlights the global importance of core training in sports physiotherapy, focusing on improving performance and minimizing injuries. The core, encompassing regions from the scapula to the gluteals, plays a crucial role in athletic performance and injury prevention. The concept…

Artificial Intelligence (AI) is becoming an essential tool in the legal field, helping lawyers analyze cases, predict legal outcomes, and even automate contracts. While these advancements improve efficiency, they also bring ethical and legal challenges. One major concern is ensuring that AI-based de…

Introduction: The use of psychoactive substances among young people is an increasing challenge in Albania, with serious impacts on their physical, mental, and social well-being. This study aims to assess the level of knowledge, attitudes, perceptions, and practical experiences of young people relate…

Despite being a common orthodontic treatment procedure, permanent tooth extraction remains a contentious issue due to its potential functional and aesthetic effects. The aim of this study is to evaluate, through a literature review, the aesthetic and functional outcomes of orthodontic treatments wit…

The aim of this article is to present the surgical treatment and rehabilitation progress of a young male patient who had suffered from bilateral neonatal osteomyelitis of the hip joints, with more severe damage on the right side. At the age of 26, the patient underwent total right hip arthroplasty, …

Literature Review: Kaposi’s Sarcoma is a vascular tumor associated with Human Herpesvirus 8 (HHV-8), which typically occurs in immunocompromised individuals. Case Report: We are reporting the case of a 67-year-old woman with a previous history of breast cancer who presented with multiple nodular pu…

Albania is facing one of the biggest technological challenges, “Artificial Intelligence”. The main legislative institution in Albania, the Albanian Parliament, has been trying to create legislation for the “embrace” of “Artificial Intelligence” in the last three years, as a condition also by the Eur…